Lead screw vs. Guide rail clampup

Greets to all:

For a generic stage design, i.e. two guide rails and a stepper driven
lead screw, is the preferred design to avoid restraining axially at
least one end of each guide rail? My thinking was that this would
enhance the accuracy, though perhaps only slightly, by eliminating
any potential guide rod deformation due to a load induced during
clamp-up or cutter engagement. Thoughts? Suggestions?


Best regards,

Ron